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  • Alcoholism is an issue which afflicts over 14 million Americans, almost 8% with the population of the United States. The majority of alcohol rehabilitation programs available today have a very low success rate, because of this many people have turned to medications as a way to limit or stop their drinking problem. Two types of medications are presently used in the treatment of alcoholics, Aversive Medications and Anticraving Medications. Using two separate drugs to shed pounds can be very effective there are combinations in front of the FDA now awaiting approval. When dealing with fat loss and the people that go through it one should err along the side of caution and allow FDA do its job and demand some research be done in order that the public is aware of the side effects and dangers of the medications before we drive them. Keep in mind that drug companies come in business to generate income and that they would say anything to keep people on the medications. Researchers discovered that participants using this drug for the year, dropped a few pounds within 4 weeks and have kept the load off throughout the 56 weeks in the study. Contrave is often a combination in the drugs naltrexone and bupropion, which appears to reflect a new trend of weight-loss drugs which are made up of many active ingredient, that might make them more efficient and safer. Combo-pilling will be the newest fad or also the newest into the future under scrutiny and for that reason it is just more publicly known lately, comb-pilling for losing weight has been around since the eighties. The biggest reason that employing a combination of pills is becoming popular could be the fact that since right now there are no long term prescription weight loss supplements that have been licensed by the FDA other than orlistat. The truly disturbing part is doctors are prescribing these combinations of medications although some people might of the combinations have been rejected or have yet to be approved by the FDA. Seizures really are a side effect with Contrave and shouldn't be taken in people with seizure disorders. The drug also can raise hypertension and heartrate, and mustn't be used in people with a history of cardiac event or stroke in the earlier six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy with all the drug. The FDA also warned that Contrave can raise blood pressure levels and pulse rate and must not be used in patients with uncontrolled high blood pressure levels, and also by anyone with heart-related and cerebrovascular (circulation dysfunction impacting mental performance) disease. Patients which has a history of cardiac event or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded through the clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes having a boxed warning to alert medical researchers and patients to the increased probability of suicidal thoughts and behaviors associated with antidepressant drugs. The warning also notes that serious neuropsychiatric events are already reported in patients taking bupropion for stopping smoking. "This could be the first drug I'm aware of that targets both the appetite and reward centres in the brain," he said.